Dermatol Clin. Jul;11(3) Epidermolysis bullosa acquisita and bullous systemic lupus erythematosus. Diseases of autoimmunity to type VII collagen. Bullous Systemic Lupus Erythematosus (BSLE) is a rare manifestation of . (BP), inflammatory variant of epidermolysis bullosa acquisita (EBA), and linear IgA. However, unlike epidermolysis bullosa acquisita, bullous systemic lupus erythematosus tends to respond dramatically to treatment with.

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Br J Dermatol,pp. Autoantibody mediated pathomechanisms regulate clinical-pathological phenotypes of acquired epidermolysisbullosa and bullous SLE. The case is presented for its typical and lhpus features which should prompt an astute physician to suspect and investigate underlying systemic manifestations of SLE.

Bullous eruption of systemic lupus erythematosus.

Bullous Systemic Lupus Erythematosus

Bullous disease in systemic lupus erythematosus. Lupus, 12pp. A lesional biopsy revealed subepidermal split with neutrophilic infiltrate in the papillary dermis [ Figure 2 ]. The course of the disease is benign with remission reported in most of the cases within a year, including ours.


Lupus Eritematoso Sistémico Bulloso en una niña de 10 años de edad. Reporte de un caso

Lesions are present on covered as well as exposed areas. Inset shows a positive lupus band IgG at the basement membrane zone. Bullous systemic lupus erythematosus: A 6-month history suggestive of Raynaud’s phenomenon; arthralgias involving small joints of hands and feet; photosensitivity; and intermittent episodes of mild to moderate fever was present.

Support Center Support Center. Int J Dermatol ; Sem Arthritis Rheum, 20pp. Continuing navigation will be considered as acceptance of this use.

Often associated is a heterogeneous profile of autoimmunity to components of type VII collagen. Even if one is not able to initiate dapsone due to relative contraindications, as in our case, every effort should be made to use it as early as possible.

Lupus Eritematoso Sistémico Bulloso en una niña de 10 años de edad. Reporte de un caso

Bylloso eruption of systemic lupus erythematosus. Based on clinical, histopathological, and serological evidence, a diagnosis of BSLE was confirmed. Systemic lupus erythematosus with vesiculobullous lesions. Hermann Pinkus memorial Lecture The disease is very responsive to dapsone therapy.


Occasionally other antigens such as laminin 5, laminin 6, and BP bullous pemphigoid antigen have also been described. Journal List Indian J Dermatol v. Bulla spread sign and Nikolsky sign were positive.

Clin Rheum Dis, 8pp. Vibeke Strand et al.

Autoimmunity to collagen VII: Her systemic examination was essentially normal. Bullous systemic lupus erythematosus with cutaneous mucinosis and leukocytoclastic vasculitis.

Vesiculobullous systemic lupus erythematosus. A report of four cases.

J Dermatol, 21pp. Epidermolysis bullosa acquisita preceding the development of systemic lupus erythematosus.